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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccb02ea1fff645cb3d85d95accd091d997a8b6a54f259de4108ebd4d3f3db150' 
  AND token = 'BWPDWPLHyFlNkN+HRNDM4EPTgO6tVAgkbMWAw20TQHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}