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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c29257df243cf726c378209fa7ace22022f9f8806758898e92e9f0bd0ecf6da4' 
  AND token = 'JVtjhR1KRRtHFBbx0omfgvWJLzC0VvLy0ndmL13laP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}