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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a37d61172d4dc981bf8676c9535008bb53e76fd50f8ba65d7393305d3a455e21' 
  AND token = '7Zzz0UTD7+klZKaGSnh5Oalbux77TOd8wOPxVHvg4rA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}