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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f186878b12a4217d13a309429aea865c862f914e429972902fa3e6590a213fe' 
  AND token = 'UBCDXnJdHPPzq8CDY7XIUEQkAuPjaE//ts8Umva0sTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}