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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27226e8270d67eded39db938567f64b6fd3d42cc351de3760600cda0a617ad15' 
  AND token = 'c00zP2ykRHvbjImTue4D6h8r5zb7qpfoh8Hxl33KmvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}