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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aeb15d852e198cb925ec5f864f049eb19c2440d11c981d1c532f5f3bef47700' 
  AND token = 'v4irFlPWuAc6gK1StJqA2/MZ9UkXilP+X1uvL3iTaKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}