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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f32445e575e25ea0e7e4c61ddb8f69e8970c4e34bc055b083f5ce3c17c87c0d' 
  AND token = 'hkD6iu/qotw+cPT0nLsAUiITQ/cU7/slyjFsKutZ2uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}