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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b160cb50d3d07abfd6e126716f6f392151e126efc1ee65e33d71fd935d5ce2dd' 
  AND token = 'ahVpmV5JTbIM1EwkfN49d7xk4L66SkwT86VVlkoF2R4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}