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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78281891fae31b34986ce769647ff81f3b1dc9fee4a093cce85221da15c7ea55' 
  AND token = 'iA2l0STKEEUXU6Jo1i4vfZg9ZGXqMpKLUF7CrSsUMNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}