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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7095a01b2cf4010b5682dd4bd4144db33d7352c8581da078f5f71e8374799ae6' 
  AND token = '/yEyesdYpyfJPZ8KIAsrMAqeqfr3DmSGL+znDdOFB0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}