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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '483c00bfd1e877ce56053181c6eb4bba299b3a29c00f243d2b427280fb2f81b3' 
  AND token = '7zrmdTP4sLSdpL7M25nwQzw1KPeESSYFulgINubBgH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}