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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3846a74a9066a79a903671408a391e7f5a591ffcf5981d4b97e3211ad2612e4e' 
  AND token = 'Absypfq8XMLkBMA3t8CyQpa6shayinNDCV389ZnaWio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}