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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '977e62e948c413208ca75e6727c4ba7b035606d2907f0b5d8476f4e9f3151aa9' 
  AND token = 'xx6N4M7ryC1AQvL2XEEMEJzFcH1kQNRX25XCdcJqiBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}