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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7748d1190406dbd30ba2c800e1b9100135104b3f3965bc1f17b02993927affef' 
  AND token = 'xVTH6W+tPqlaQwan4rFxseFSi2PJPhvWLCYLP856kU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}