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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ec0b89e4a502c9823f7c3fd3f94cd17c05207c6558dcc4395d144e2734472b3' 
  AND token = 'ecbB7+gWlO851vv+Ks4XKtqwx9Ilw8z9jHKm0m402sE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}