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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fa22542be7c9a497b3b62281ee6f6e3ce863030d731acbf73c28e7e6469e78e' 
  AND token = 'N+DYA7mX0+ZhkeCTWM2KW/HuWHev1pqaPatwxb1ZbfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}