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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37712820f474c9fd1a46bb83ea621e7a66353599844173699224a714271d7283' 
  AND token = 'Cfv8eXr4Bu6SSOJAXMcKMaD17MtIhDCpTJGGg7I8LX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}