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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7299beaa614684d3da62c293dc636058f81cfdcbfcf034b85b09675820918886' 
  AND token = 'b+mZk3EaIR3Mc01FLf8ORSfRhIaGJ2VEOErDy/cSo0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}