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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e42a96d2bdb2ec8ac7b8d3662dda3bab9b367c1157f78a2c653b3df03f2905aa' 
  AND token = 'QrJd8NXjSZULlIeXa4mseaj7FRQv5TWQVG6fZ4OIn7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}