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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2b8c2049e21f688a08f1b77e1a04db1518d794f16b97bb48a6f12f9df49b315' 
  AND token = 'VorarUpkt5C0r3BUdbZF8M3JlUidQWcdwSZGNc8RnXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}