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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f2fc80437c8f0f5b623b07ef13e3e5ebf1695360a0e9eec5ebb1e9723b2cdfb' 
  AND token = 'nBZtYBDXV8IwdiQ/9Dt7vQfFCHwnneFV8cahZJEO4Mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}