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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74e73685126b4ca37ed47aa2e433f6b1f8c8a6fe013046bf847c9ce2c42d6e0d' 
  AND token = 'kIZOHXfi5esD4LK1Yo516ZK6GJo8glvZ5eQ8IjJSivc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}