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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5607baf6ca64a30a35bfad98b0dc9bb40b7f4c4c186022bdc0f9479de38f141b' 
  AND token = 'me0P8V8+gOEeJ+bqLobCQr9pUSDCdzUUnxTUyyTdHr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}