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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f244e911c213f95fd15e2cf63f1b45417f37445a1b16bf5debc98cf3db0f2f3' 
  AND token = 'ItY7SsQyj0mrEX0GuzkLcz1Rn3ubZhEDm7fHN41ImhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}