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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e800e209a055c9dd69ab6b674f10cda8dc941ed1a52cccf7d871f71068534b05' 
  AND token = 'uMlut78Hbyownt2qTGTI2+WptEzyBkL8SAQMk2a646A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}