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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47729b3d3b8fbeef34aa330cbac2e0f219a4b7d91029a3266215fe7d893b94d2' 
  AND token = 'iUfs18gHgCbzGNmU42B7VxS/06CeR9qv23upoqDhsmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}