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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd080c69671b0889eb6bffcb4a661d4cb1964dd010a1804565a9ecbd97348438c' 
  AND token = 'xj0yD3bGXsP9fc1GDVzw7S2VFYuH/QEa5ePEFQiW35g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}