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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '504b6c68cabb520686dd067a5c4d4dfe7fc110160d523124092230945cc560f4' 
  AND token = 'c9RAbKBN08Y/Nwcm4LESOvnn/9n8x19smzldm+hnDuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}