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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7166f5285b4252c58f8d3b79c34e4173a4a76b0a9dce26a880e06a254039f3e6' 
  AND token = 'UH6iXsQFFcWoC1Fg5ih95Lvji8PWzIhVWUf27hChf/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}