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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69a9f82a8564f2b9960c9cc2f5681e4cdd48377f66fb74de285d1e918789cef8' 
  AND token = 'IBodQAQ6D+SEo43PPZ08fSsqLx9HmugB8Iv5ow8bKLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}