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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd56763954763f40df95967db39a000da2c304d0d1bf2be8afe858701cb4d69ea' 
  AND token = 'UOK5tdmAUSVkFWqfS7TpMZWlnckhLidvnkXQI5QgZRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}