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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fd9f51cb3e45df3585bbbfb499a38114c922b41b1186845e2fe207b9e9a193f' 
  AND token = 'g+K29+74KVw7Q44gUR9ZhOTy8c3wwbgEbUtTBHLVcNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}