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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bd677d4a6a8a80c306a74af2ac51e78cd1988b830bf5c827b369d249fba3c79' 
  AND token = 'UITtuIvhkAFujxHVi3a+Xo5vna4v/EwR5CY1cFlzoL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}