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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6caa99fe5b2f68d99f552f5360b0cba1720c11dc69bc980977a01d822baf85d7' 
  AND token = 'VDpg5bM121mUAeeHw/l4y+tiU+QNiqfRo6sGawygDQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}