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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1424c8a3111ef9b37e09cefb1579077efd6b34150a16083860fb185b3b29dc4' 
  AND token = 'PLtG/X7PcN4QAzcUy6rjQC+hqvA5KbxzT8yjURaei4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}