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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecca3c51574f3433fce9e3e42b7f230c175d2d72f1b1d2ef44605e78e405e025' 
  AND token = 'juKONXwHuETWtxJn+9npID1L9MDJ8/TT2Zy6E4BnD78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}