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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ecea9278ef0e00a7a33512eee86fa78b263a9a0102624e9f3429d61f913eaf9' 
  AND token = 'b3Jv1rFQxcJjawYg+Ae4UePOFN24793oLzw2nubUg1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}