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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7333d14e4bd4691b28f3762f51e07563f4d4a0980b6d2bf6d71becfce68c41d6' 
  AND token = 'F8/iL4lHvKFscoERzw0gLeO1HO2PkrJKbfJdfHgAYm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}