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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74b810f0aaaaa474a27e181c87c91b2a178617ad90a13971c51086d372b86eb4' 
  AND token = 'aXmA6GpolVEr1tqCmOZrrT1nPAB6G+eXy/1ok1vB5cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}