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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b019f4a9bd17037ff163b9568664f3de6347199e0c54b659f0bdfa2707671935' 
  AND token = 'gHnH1bzyySW+kLQF1YqZgdWRE4OGVPjC3P5n4H2Wbt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}