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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2228aa779c9f3db6e6903470a56d1f71b40eb69bf5e271197ee2fe0f0b80ece' 
  AND token = '8UnATqArFEx/kH5Jw6V9J9MfSuJJa50IhkUAV9jP+Cs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}