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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3ac6e6f9bfb943901f523de029f5c678b4599d9f8aa6de04e6af637d377e700' 
  AND token = 'iNm1WrbuV30AWtisx3aD9eFc/npn91DPkcfhwckCVNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}