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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a007603271f960b34daad5b7633ba3f121d590e4cf505b7e033347103808e18a' 
  AND token = 'QBMkHBbYOS+TaynPRuvP/xNIpzqMo+BD4M7757SmKl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}