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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '949e460c2aced1cbc04f6e05bfdafc2b60ad8c1b5e8fcc28954f9de9515ca500' 
  AND token = 'jvP/69kcX7X+Jlwt1hTevWzjswGfMkGaH576mzMcfLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}