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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dbd66d0db6a55b92ac506c8f63ef3bb1f3bf5c36d7faf1ef4e4734eb69f5111' 
  AND token = '2jFyZyUuUv6rQ9pCOMeJhnPJAVewy5u2N2Bs0o7OrIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}