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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b02111b53594fcc8c80be1f4643de8229c5f76c00ceb704cd176294300356b1' 
  AND token = 'LxtlG7aANq2pK379IZIBBkm52VXVrifXMUeSU8hkVR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}