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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f5b97d22e5127a54ea7627a1b61d4daecc16c60219b584766df8276de48958f' 
  AND token = 'P9sp/fjDU0nPV2U3OpjeG+hchLqRkruPO2cv+Pupkqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}