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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4576c887c1f25d859b6e9b24b1824bc2854a31481ce64932b398ff90deabcbb2' 
  AND token = 'toHcAXZAIwq7Hep5nHK83V5jMs0MmhzPN0knvt7YGPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}