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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11e20e12648b7b06ac57cbf5a3a70192e078d7be4c243bc2f6677d41b0505e00' 
  AND token = 'tXNH7SQvctBOR3OcKlRZXQYfqCIRShZg8nKM9N5GFbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}