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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b6e1bbe8351ab66cd3f1cd6b6802543e01698e51766dbf3540d104efcda1d8a' 
  AND token = 'Eh2Sjq0HArUtKnkYvhDqfG8LqNrW+txh7cjVv4KQP4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}